William Michael Carson

Photo (circa `93), and ribbons demo used (for 2 seconds) in the movie Jurassic Park.

Biographical Sketch

Mike Carson (b. 1951) received a BS in chemistry from the University of Arkansas (1973) and a PhD in chemistry from the University of Texas (1980) for research in protein crystallography under the direction of Marvin Hackert. Postdoctoral work was done in crystallography in Robert Huber's lab at the Max Planck Institute for Biochemistry at Munich and in computational chemistry and molecular graphics with Jan Hermans at the University of North Carolina. He retired in late 2005 as an associate scientist with the Center for Biophysical Sciences and Engineering (formerly Center for Macromolecular Crystallography), research associate professor of Biomedical Engineering and an adjunct faculty member of the Computer Information Sciences department at the University of Alabama at Birmingham. His research interests include protein structure, bioinformatics, computational methods, scientific visualization, and structure-based drug design. Outside interests include music, cooking, hiking, and the Razorbacks.

Research

See Best publications and images on-line.
See CV for a complete list of publications.
See resume for more details.

Bioinformatics
Latest big project is structural genomics, with the development of the database known internally as the Can Of Worms.


Scientific Visualization
Virtual Reality Modeling Language methods to produce music from molecules.
Ongoing development of the ribbons program.
Image from SIGGGRAPH slide set.


Protein Structure
Determination and analysis of the 3-D atomic-level structures in collaboration with Center scientists.
Two monthly cover images in the year 2000.


Structure-based Drug Design
Work on drug design teams targeting PNP, viral neuraminidase, and human complement Factor D. PNP image from cover of Acta Crystallographica. Currently working on targets related to malaria and anthrax.


Computational Methods
Wavelets and molecular structure; Crystallographic error analysis. Image from publication on wavelets in Computer-Aided Molecular Design.


Contact

See CV for postal address/phone numbers.
Email: carson@uab.edu